Human ARHGEF9 activation kit by CRISPRa

SKU
GA108143
ARHGEF9 CRISPRa kit - CRISPR gene activation of human Cdc42 guanine nucleotide exchange factor 9
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARHGEF9
Locus ID 23229
Components

GA108143G1, ARHGEF9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108143G2, ARHGEF9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108143G3, ARHGEF9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001173479, NM_001173480, NM_001330495, NM_015185, NM_001353921, NM_001353922, NM_001353923, NM_001353924, NM_001353926, NM_001353927, NM_001353928, NM_001369031, NM_001369036, NM_001369037, NM_001369039, NM_001369041, NM_001369043, NM_001369044, NM_001369045, NM_001369030, NM_001369032, NM_001369033, NM_001369034, NM_001369035, NM_001369038, NM_001369040, NM_001369042
UniProt ID O43307
Synonyms COLLYBISTIN; EIEE8; HPEM-2; PEM-2; PEM2
Summary The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN416681 ARHGEF9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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