Human JIP3 (MAPK8IP3) activation kit by CRISPRa

SKU
GA108084
MAPK8IP3 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase 8 interacting protein 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAPK8IP3
Locus ID 23162
Components

GA108084G1, JIP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108084G2, JIP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108084G3, JIP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001040439, NM_001318852, NM_015133, NM_033392
UniProt ID Q9UPT6
Synonyms JIP-3; JIP3; JSAP1; syd; SYD2
Summary The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN413840 MAPK8IP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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