Human NACAD activation kit by CRISPRa

SKU GA108073

NACAD CRISPRa kit - CRISPR gene activation of human NAC alpha domain containing

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NACAD
• Locus ID: 23148
• Components:

  GA108073G1, NACAD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108073G2, NACAD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108073G3, NACAD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001146334
• UniProt ID: O15069
• Synonyms: KIAA0363
• Summary: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).[UniProtKB/Swiss-Prot Function]