Human PHF8 activation kit by CRISPRa

SKU
GA108062
PHF8 CRISPRa kit - CRISPR gene activation of human PHD finger protein 8
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PHF8
Locus ID 23133
Components

GA108062G1, PHF8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108062G2, PHF8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108062G3, PHF8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001184896, NM_001184897, NM_001184898, NM_015107
UniProt ID Q9UPP1
Synonyms JHDM1F; MRXSSD; ZNF422
Summary The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2017
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Other Versions
SKU Description Size Price
KN414763 PHF8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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