Human PPRC1 activation kit by CRISPRa

SKU GA108024

PPRC1 CRISPRa kit - CRISPR gene activation of human PPARG related coactivator 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PPRC1
• Locus ID: 23082
• Components:

  GA108024G1, PPRC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108024G2, PPRC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108024G3, PPRC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001288727, NM_001288728, NM_015062
• UniProt ID: Q5VV67
• Synonyms: PRC
• Summary: The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]