Human HECW1 activation kit by CRISPRa

SKU
GA108016
HECW1 CRISPRa kit - CRISPR gene activation of human HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HECW1
Locus ID 23072
Components

GA108016G1, HECW1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108016G2, HECW1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108016G3, HECW1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001287059, NM_015052
UniProt ID Q76N89
Synonyms NEDL1
Summary E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN413181 HECW1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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