Human PLA2R (PLA2R1) activation kit by CRISPRa

SKU GA107916

PLA2R1 CRISPRa kit - CRISPR gene activation of human phospholipase A2 receptor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PLA2R1
• Locus ID: 22925
• Components:

  GA107916G1, PLA2R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107916G2, PLA2R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107916G3, PLA2R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001007267, NM_001195641, NM_007366
• UniProt ID: Q13018
• Synonyms: CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
• Summary: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]