Human PUF60 activation kit by CRISPRa

SKU
GA107835
PUF60 CRISPRa kit - CRISPR gene activation of human poly(U) binding splicing factor 60
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PUF60
Locus ID 22827
Components

GA107835G1, PUF60 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107835G2, PUF60 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107835G3, PUF60 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136033, NM_001271096, NM_001271097, NM_001271098, NM_001271099, NM_001271100, NM_014281, NM_078480, NM_001362895, NM_001362897, NM_001362896
UniProt ID Q9UHX1
Synonyms FIR; RoBPI; SIAHBP1; VRJS
Summary This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Aug 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN403454 PUF60 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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