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Human IKZF3 activation kit by CRISPRa

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SKU
GA107823
IKZF3 CRISPRa kit - CRISPR gene activation of human IKAROS family zinc finger 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA804396 IKZF3 mouse monoclonal antibody, clone OTI7E11 (formerly 7E11) 100 ul
$447.00
RC207547 IKZF3 (Myc-DDK-tagged)-Human IKAROS family zinc finger 3 (Aiolos) (IKZF3), transcript variant 1
10 ug
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Other products for "IKZF3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IKZF3
Locus ID 22806
Components

GA107823G1, IKZF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107823G2, IKZF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107823G3, IKZF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001257408, NM_001257409, NM_001257410, NM_001257411, NM_001257412, NM_001257413, NM_001257414, NM_001284514, NM_001284515, NM_001284516, NM_012481, NM_183228, NM_183229, NM_183230, NM_183231, NM_183232, NR_047559, NR_047560, NR_047561
UniProt ID Q9UKT9
Synonyms AIO; AIOLOS; ZNFN1A3
Summary This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. provided by RefSeq, Apr 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN407547 IKZF3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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