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Human MAN1B1 activation kit by CRISPRa

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SKU
GA107754
MAN1B1 CRISPRa kit - CRISPR gene activation of human mannosidase alpha class 1B member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC202824 MAN1B1 (Myc-DDK-tagged)-Human mannosidase, alpha, class 1B, member 1 (MAN1B1)
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Other products for "MAN1B1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAN1B1
Locus ID 11253
Components

GA107754G1, MAN1B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107754G2, MAN1B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107754G3, MAN1B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007230, NM_016219, NR_045720, NR_045721
UniProt ID Q9UKM7
Synonyms DKFZP434I213; MANA-ER
Summary This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. provided by RefSeq, Dec 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN402824 MAN1B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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