Human AKAP11 activation kit by CRISPRa

SKU GA107725

AKAP11 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 11

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: AKAP11
• Locus ID: 11215
• Components:

  GA107725G1, AKAP11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107725G2, AKAP11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107725G3, AKAP11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_016248, NM_144490
• UniProt ID: Q9UKA4
• Synonyms: AKAP-11; AKAP220; PPP1R44; PRKA11
• Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]