Human DMC1 activation kit by CRISPRa

SKU GA107667

DMC1 CRISPRa kit - CRISPR gene activation of human DNA meiotic recombinase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DMC1
• Locus ID: 11144
• Components:

  GA107667G1, DMC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107667G2, DMC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107667G3, DMC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001278208, NM_007068, NR_103474, NM_001363017
• UniProt ID: Q14565
• Synonyms: dJ199H16.1; DMC1H; LIM15
• Summary: This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]