Human IL1RAPL1 activation kit by CRISPRa

SKU
GA107664
IL1RAPL1 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor accessory protein like 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL1RAPL1
Locus ID 11141
Components

GA107664G1, IL1RAPL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107664G2, IL1RAPL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107664G3, IL1RAPL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014271
UniProt ID Q9NZN1
Synonyms IL1R8; IL1RAPL; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2
Summary The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN411816 IL1RAPL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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