Human PRDM4 activation kit by CRISPRa

SKU GA107640

PRDM4 CRISPRa kit - CRISPR gene activation of human PR/SET domain 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRDM4
• Locus ID: 11108
• Components:

  GA107640G1, PRDM4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107640G2, PRDM4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107640G3, PRDM4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_012406
• UniProt ID: Q9UKN5
• Synonyms: PFM1
• Summary: The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]