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Human SF3B2 activation kit by CRISPRa

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SKU
GA107548
SF3B2 CRISPRa kit - CRISPR gene activation of human splicing factor 3b subunit 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "SF3B2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SF3B2
Locus ID 10992
Components

GA107548G1, SF3B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107548G2, SF3B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107548G3, SF3B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006842
UniProt ID Q13435
Synonyms Cus1; SAP145; SF3b1; SF3B145; SF3b150
Summary This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN422762 SF3B2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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