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Human MMP24 activation kit by CRISPRa

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SKU
GA107464
MMP24 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 24
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$205.00
RC222100 MMP24 (Myc-DDK-tagged)-Human matrix metallopeptidase 24 (membrane-inserted) (MMP24)
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Other products for "MMP24"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMP24
Locus ID 10893
Components

GA107464G1, MMP24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107464G2, MMP24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107464G3, MMP24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006690
UniProt ID Q9Y5R2
Synonyms MMP-24; MMP25; MT-MMP 5; MT-MMP5; MT5-MMP; MT5MMP; MTMMP5
Summary This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase). The gene has previously been referred to as MMP25 but has been renamed matrix metallopeptidase 24 (MMP24). provided by RefSeq, Oct 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN422100 MMP24 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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