Human MSF (SEPT9) activation kit by CRISPRa

SKU GA107402

SEPTIN9 CRISPRa kit - CRISPR gene activation of human septin 9

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SEPTIN9
• Locus ID: 10801
• Components:

  GA107402G1, MSF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107402G2, MSF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107402G3, MSF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001113491, NM_001113492, NM_001113493, NM_001113494, NM_001113495, NM_001113496, NM_001293695, NM_001293696, NM_001293697, NM_001293698, NM_006640
• UniProt ID: Q9UHD8
• Synonyms: AF17q25; MSF; MSF1; NAPB; PNUTL4; SeptD1; SINT1
• Summary: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]