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Human CLDN16 activation kit by CRISPRa

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SKU
GA107327
CLDN16 CRISPRa kit - CRISPR gene activation of human claudin 16
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210216 CLDN16 (Myc-DDK-tagged)-Human claudin 16 (CLDN16)
10 ug
$289.00 $300.00

Other products for "CLDN16"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CLDN16
Locus ID 10686
Components

GA107327G1, CLDN16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107327G2, CLDN16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107327G3, CLDN16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006580
UniProt ID Q9Y5I7
Synonyms HOMG3; PCLN1
Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. provided by RefSeq, Jun 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN410216 CLDN16 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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