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Human CTCF activation kit by CRISPRa

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SKU
GA107311
CTCF CRISPRa kit - CRISPR gene activation of human CCCTC-binding factor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA375185 CTCF Rabbit polyclonal Antibody
100 ul
$410.00
RC202416 CTCF (Myc-DDK-tagged)-Human CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 1
10 ug
$665.00

Other products for "CTCF"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CTCF
Locus ID 10664
Components

GA107311G1, CTCF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107311G2, CTCF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107311G3, CTCF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001191022, NM_006565, NM_001363916
UniProt ID P49711
Synonyms MRD21
Summary This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN202416 CTCF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202416BN CTCF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202416LP CTCF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202416RB CTCF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402416 CTCF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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