Human TXNIP activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | TXNIP |
| Locus ID | 10628 |
| Components |
GA107279G1, TXNIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107279G2, TXNIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107279G3, TXNIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001313972, NM_006472 |
| UniProt ID | Q9H3M7 |
| Synonyms | ARRDC6; EST01027; HHCPA78; THIF; VDUP1 |
| Summary | This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN210804 | TXNIP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN210804BN | TXNIP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN210804LP | TXNIP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN210804RB | TXNIP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN410804 | TXNIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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