Human ARID3B activation kit by CRISPRa

SKU GA107272

ARID3B CRISPRa kit - CRISPR gene activation of human AT-rich interaction domain 3B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ARID3B
• Locus ID: 10620
• Components:

  GA107272G1, ARID3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107272G2, ARID3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107272G3, ARID3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001307939, NM_006465
• UniProt ID: Q8IVW6
• Synonyms: BDP; DRIL2
• Summary: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]