Human STK25 activation kit by CRISPRa

SKU GA107169

STK25 CRISPRa kit - CRISPR gene activation of human serine/threonine kinase 25

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: STK25
• Locus ID: 10494
• Components:

  GA107169G1, STK25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107169G2, STK25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107169G3, STK25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001271977, NM_001271978, NM_001271979, NM_001271980, NM_001282305, NM_001282306, NM_001282307, NM_001282308, NM_006374, NR_073530, NR_073531, NR_073532, NR_073533
• UniProt ID: O00506
• Synonyms: SOK1; YSK1
• Summary: This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]