Human ABCA9 activation kit by CRISPRa

SKU GA107055

ABCA9 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily A member 9

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ABCA9
• Locus ID: 10350
• Components:

  GA107055G1, ABCA9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107055G2, ABCA9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107055G3, ABCA9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_080283, NM_172386
• UniProt ID: Q8IUA7
• Synonyms: EST640918
• Summary: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]