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Human TLR6 activation kit by CRISPRa

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SKU
GA107045
TLR6 CRISPRa kit - CRISPR gene activation of human toll like receptor 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "TLR6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TLR6
Locus ID 10333
Components

GA107045G1, TLR6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107045G2, TLR6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107045G3, TLR6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006068
UniProt ID Q9Y2C9
Synonyms CD286
Summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.provided by RefSeq, Jan 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN415761 TLR6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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