Human RAMP2 activation kit by CRISPRa

SKU
GA106990
RAMP2 CRISPRa kit - CRISPR gene activation of human receptor activity modifying protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RAMP2
Locus ID 10266
Components

GA106990G1, RAMP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106990G2, RAMP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106990G3, RAMP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_005854
UniProt ID O60895
Summary The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. provided by RefSeq, Jul 2008
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Resources
Other Versions
SKU Description Size Price
KN206531 RAMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN206531BN RAMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN206531LP RAMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206531RB RAMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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