Human RPP20 (POP7) activation kit by CRISPRa

SKU GA106976

POP7 CRISPRa kit - CRISPR gene activation of human POP7 homolog, ribonuclease P/MRP subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: POP7
• Locus ID: 10248
• Components:

  GA106976G1, RPP20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106976G2, RPP20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106976G3, RPP20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005837
• UniProt ID: O75817
• Synonyms: 0610037N12Rik; RPP2; RPP20
• Summary: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).[UniProtKB/Swiss-Prot Function]