Human BMP11 (GDF11) activation kit by CRISPRa

SKU
GA106950
GDF11 CRISPRa kit - CRISPR gene activation of human growth differentiation factor 11
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GDF11
Locus ID 10220
Components

GA106950G1, BMP11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106950G2, BMP11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106950G3, BMP11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005811
UniProt ID O95390
Synonyms BMP-11; BMP11
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. provided by RefSeq, Aug 2016
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Other Versions
SKU Description Size Price
KN422080 GDF11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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