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Human RASGRP1 activation kit by CRISPRa

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SKU
GA106869
RASGRP1 CRISPRa kit - CRISPR gene activation of human RAS guanyl releasing protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC212473 RASGRP1 (Myc-DDK-tagged)-Human RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1
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Other products for "RASGRP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RASGRP1
Locus ID 10125
Components

GA106869G1, RASGRP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106869G2, RASGRP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106869G3, RASGRP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001128602, NM_001306086, NM_005739
UniProt ID O95267
Synonyms CALDAG-GEFI; CALDAG-GEFII; hRasGRP1; RASGRP; V
Summary This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN412473 RASGRP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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