Human PQBP1 activation kit by CRISPRa

SKU GA106836

PQBP1 CRISPRa kit - CRISPR gene activation of human polyglutamine binding protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PQBP1
• Locus ID: 10084
• Components:

  GA106836G1, PQBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106836G2, PQBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106836G3, PQBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001032381, NM_001032382, NM_001032383, NM_001032384, NM_001032385, NM_001167989, NM_001167990, NM_001167992, NM_005710, NM_144494, NM_144495
• UniProt ID: O60828
• Synonyms: MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; SHS
• Summary: This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]