Human DPP3 activation kit by CRISPRa

SKU GA106826

DPP3 CRISPRa kit - CRISPR gene activation of human dipeptidyl peptidase 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DPP3
• Locus ID: 10072
• Components:

  GA106826G1, DPP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106826G2, DPP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106826G3, DPP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001256670, NM_005700, NM_130443
• UniProt ID: Q9NY33
• Synonyms: DPPIII
• Summary: This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]