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Human BCL2L10 activation kit by CRISPRa

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SKU
GA106785
BCL2L10 CRISPRa kit - CRISPR gene activation of human BCL2 like 10
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC211604 BCL2L10 (Myc-DDK-tagged)-Human BCL2-like 10 (apoptosis facilitator) (BCL2L10)
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Other products for "BCL2L10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCL2L10
Locus ID 10017
Components

GA106785G1, BCL2L10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106785G2, BCL2L10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106785G3, BCL2L10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001306168, NM_020396
UniProt ID Q9HD36
Synonyms BCL-B; Boo; Diva
Summary The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN411604 BCL2L10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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