Human NR1D2 activation kit by CRISPRa

SKU GA106752

NR1D2 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 1 group D member 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NR1D2
• Locus ID: 9975
• Components:

  GA106752G1, NR1D2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106752G2, NR1D2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106752G3, NR1D2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001145425, NM_005126, NR_110524
• UniProt ID: Q14995
• Synonyms: BD73; EAR-1R; RVR
• Summary: This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]