Human ENDOGL1 (EXOG) activation kit by CRISPRa

SKU GA106724

EXOG CRISPRa kit - CRISPR gene activation of human exo/endonuclease G

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: EXOG
• Locus ID: 9941
• Components:

  GA106724G1, ENDOGL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106724G2, ENDOGL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106724G3, ENDOGL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001145464, NM_001318954, NM_001318955, NM_001318956, NM_001318957, NM_001318958, NM_001318959, NM_005107, NR_134938, NR_153322, NR_153323, NR_153324, NR_153325, NR_153326, NR_153327, NR_153328, NR_153329, NR_153330
• UniProt ID: Q9Y2C4
• Synonyms: ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB
• Summary: This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]