Human DENND4B activation kit by CRISPRa

SKU GA106695

DENND4B CRISPRa kit - CRISPR gene activation of human DENN domain containing 4B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DENND4B
• Locus ID: 9909
• Components:

  GA106695G1, DENND4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106695G2, DENND4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106695G3, DENND4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014856, NM_001367466
• UniProt ID: O75064
• Synonyms: KIAA0476
• Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.[UniProtKB/Swiss-Prot Function]