Human ARHGAP11A activation kit by CRISPRa

SKU
GA106620
ARHGAP11A CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 11A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARHGAP11A
Locus ID 9824
Components

GA106620G1, ARHGAP11A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106620G2, ARHGAP11A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106620G3, ARHGAP11A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001286479, NM_001286480, NM_014783, NM_199357
UniProt ID Q6P4F7
Synonyms GAP (1-12)
Summary This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. provided by RefSeq, Feb 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN401876 ARHGAP11A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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