Human SNX17 activation kit by CRISPRa

SKU GA106587

SNX17 CRISPRa kit - CRISPR gene activation of human sorting nexin 17

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SNX17
• Locus ID: 9784
• Components:

  GA106587G1, SNX17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106587G2, SNX17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106587G3, SNX17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001267059, NM_001267060, NM_001267061, NM_014748, NR_049782, NR_049783, NR_049784, NR_049785, NR_049786, NR_049787, NR_049788
• UniProt ID: Q15036
• Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]