Human RAPGEF5 activation kit by CRISPRa

SKU
GA106575
RAPGEF5 CRISPRa kit - CRISPR gene activation of human Rap guanine nucleotide exchange factor 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RAPGEF5
Locus ID 9771
Components

GA106575G1, RAPGEF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106575G2, RAPGEF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106575G3, RAPGEF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_012294, NM_001367600, NM_001367602, NM_001367601, NM_001367603
UniProt ID Q92565
Synonyms GFR; MR-GEF; REPAC
Summary Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 PubMed 10934204).supplied by OMIM, Mar 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN418010 RAPGEF5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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