Human SNPH activation kit by CRISPRa

SKU GA106558

SNPH CRISPRa kit - CRISPR gene activation of human syntaphilin

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SNPH
• Locus ID: 9751
• Components:

  GA106558G1, SNPH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106558G2, SNPH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106558G3, SNPH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001318234, NM_014723
• UniProt ID: O15079
• Summary: Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]