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Human Rubicon (RUBCN) activation kit by CRISPRa

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SKU
GA106521
RUBCN CRISPRa kit - CRISPR gene activation of human rubicon autophagy regulator
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA349091 Rabbit Polyclonal Anti-Rubicon Antibody
100 ug
$640.00
RC220593 KIAA0226 (Myc-DDK-tagged)-Human KIAA0226 (KIAA0226), transcript variant 2
10 ug
$1,335.00

Other products for "RUBCN"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RUBCN
Locus ID 9711
Components

GA106521G1, Rubicon gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106521G2, Rubicon gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106521G3, Rubicon gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001145642, NM_014687, NM_001346873
UniProt ID Q92622
Synonyms RUBICON; SCAR15
Summary The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Apr 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN420593 KIAA0226 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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