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Human HERPUD1 activation kit by CRISPRa

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SKU
GA106519
HERPUD1 CRISPRa kit - CRISPR gene activation of human homocysteine inducible ER protein with ubiquitin like domain 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA507019 Purified HERPUD1 mouse monoclonal antibody, clone OTI1A2 (formerly 1A2) 100 ul
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RC217811 HERPUD1 (Myc-DDK-tagged)-Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 (HERPUD1), transcript variant 3
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Other products for "HERPUD1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HERPUD1
Locus ID 9709
Components

GA106519G1, HERPUD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106519G2, HERPUD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106519G3, HERPUD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001010989, NM_001010990, NM_001272103, NM_014685
UniProt ID Q15011
Synonyms HERP; Mif1; SUP
Summary The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. provided by RefSeq, Jan 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN400693 HERPUD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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