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Human RAPGEF2 activation kit by CRISPRa

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SKU
GA106504
RAPGEF2 CRISPRa kit - CRISPR gene activation of human Rap guanine nucleotide exchange factor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC222055 RAPGEF2 (Myc-DDK-tagged)-Human Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RAPGEF2
Locus ID 9693
Components

GA106504G1, RAPGEF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106504G2, RAPGEF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106504G3, RAPGEF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014247, NM_001351724, NM_001351725, NM_001351726, NM_001351727, NM_001351728
UniProt ID Q9Y4G8
Synonyms CNrasGEF; NRAPGEP; nRap GEP; PDZ-GEF1; PDZGEF1; RA-GEF; RA-GEF-1; Rap-GEP
Summary Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 PubMed 10934204).supplied by OMIM, Mar 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN422055 RAPGEF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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