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Human PPM1F activation kit by CRISPRa

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SKU
GA106464
PPM1F CRISPRa kit - CRISPR gene activation of human protein phosphatase, Mg2+/Mn2+ dependent 1F
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA351551 Rabbit Polyclonal Anti-PPM1F Antibody
100 ul
$205.00
RC210043 PPM1F (Myc-DDK-tagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1F (PPM1F)
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Other products for "PPM1F"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PPM1F
Locus ID 9647
Components

GA106464G1, PPM1F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106464G2, PPM1F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106464G3, PPM1F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014634, N34773
UniProt ID P49593
Synonyms CAMKP; CaMKPase; FEM-2; hFEM-2; POPX2
Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN410043 PPM1F - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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