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Human RIN1 activation kit by CRISPRa

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SKU
GA106434
RIN1 CRISPRa kit - CRISPR gene activation of human Ras and Rab interactor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA314944 Rabbit polyclonal anti-RIN1 antibody
100 ul
$380.00
RC204147 RIN1 (Myc-DDK-tagged)-Human Ras and Rab interactor 1 (RIN1)
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Other products for "RIN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RIN1
Locus ID 9610
Components

GA106434G1, RIN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106434G2, RIN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106434G3, RIN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004292, NM_001363560, NM_001363559
UniProt ID Q13671
Summary Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN404147 RIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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