Human WTAP activation kit by CRISPRa

SKU GA106423

WTAP CRISPRa kit - CRISPR gene activation of human WT1 associated protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: WTAP
• Locus ID: 9589
• Components:

  GA106423G1, WTAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106423G2, WTAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106423G3, WTAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001270531, NM_001270532, NM_001270533, NM_004906, NM_152857, NM_152858
• UniProt ID: Q15007
• Synonyms: Mum2
• Summary: The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]