Human ENTPD4 activation kit by CRISPRa

SKU GA106417

ENTPD4 CRISPRa kit - CRISPR gene activation of human ectonucleoside triphosphate diphosphohydrolase 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ENTPD4
• Locus ID: 9583
• Components:

  GA106417G1, ENTPD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106417G2, ENTPD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106417G3, ENTPD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001128930, NM_004901
• UniProt ID: Q9Y227
• Synonyms: LALP70; LAP70; LYSAL1; NTPDase-4; UDPase
• Summary: This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]