Human POLR1C activation kit by CRISPRa

SKU GA106378

POLR1C CRISPRa kit - CRISPR gene activation of human RNA polymerase I and III subunit C

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: POLR1C
• Locus ID: 9533
• Components:

  GA106378G1, POLR1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106378G2, POLR1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106378G3, POLR1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004875, NM_203290, NM_001318876, NM_001363658
• UniProt ID: O15160
• Synonyms: RP3-337H4.4; RPA5; RPA39; RPA40; RPAC1; TCS3
• Summary: The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]