Human MPDU1 activation kit by CRISPRa

SKU GA106371

MPDU1 CRISPRa kit - CRISPR gene activation of human mannose-P-dolichol utilization defect 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MPDU1
• Locus ID: 9526
• Components:

  GA106371G1, MPDU1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106371G2, MPDU1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106371G3, MPDU1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004870, NR_024603, NM_001330073
• UniProt ID: O75352
• Synonyms: CDGIF; HBEBP2BPA; Lec35; My008; PP3958; PQLC5; SL15
• Summary: This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]