Human AKAP7 activation kit by CRISPRa

SKU GA106322

AKAP7 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 7

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: AKAP7
• Locus ID: 9465
• Components:

  GA106322G1, AKAP7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106322G2, AKAP7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106322G3, AKAP7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004842, NM_016377, NM_138633
• UniProt ID: O43687
• Synonyms: AKAP15; AKAP18
• Summary: This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]