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Human CYP7B1 activation kit by CRISPRa

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SKU
GA106288
CYP7B1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 7 subfamily B member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC222647 CYP7B1 (Myc-DDK-tagged)-Human cytochrome P450, family 7, subfamily B, polypeptide 1 (CYP7B1)
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CYP7B1
Locus ID 9420
Components

GA106288G1, CYP7B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106288G2, CYP7B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106288G3, CYP7B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001324112, NM_004820
UniProt ID O75881
Synonyms CBAS3; CP7B; SPG5A
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. provided by RefSeq, Apr 2016
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Documents
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Other Versions
SKU Description Size Price
KN422647 CYP7B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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