Human LONP1 activation kit by CRISPRa

SKU
GA106242
LONP1 CRISPRa kit - CRISPR gene activation of human lon peptidase 1, mitochondrial
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LONP1
Locus ID 9361
Components

GA106242G1, LONP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106242G2, LONP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106242G3, LONP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001276479, NM_001276480, NM_004793, NR_076392
UniProt ID P36776
Synonyms CODASS; hLON; LON; LonHS; LONP; PIM1; PRSS15
Summary This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Feb 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN400359 LONP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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